Increasingly, government agencies and non-profit organisations are called on to address challenges that go well beyond any individual organisation’s boundaries and direct control. Strategic management for single organisations cannot respond effectively to these cross- boundary, cross-level, and often cross-sector challenges. Instead, a new approach called strategy management-at-scale is required. This article compares strategic management with strategy management- at-scale. It responds to the question, what does strategy management- at-scale look like, and what seems to contribute to its success? The new approach helps foster – but hardly guarantees – direction, alignment and commitment among the multiple organisations and groups needed to make headway against the challenge.